PTU Syllabus 2014
The distance Education courses offered by PTU are gaining popularity especially in the field of Biotechnology. This article provide complete syllabus of B.Sc. Biotechnology (BSCBT) offered by PTU in Distance Learning Mode.
The distance Education courses offered by PTU are gaining popularity especially in the field of Biotechnology. This article provide complete syllabus of B.Sc. Biotechnology (BSCBT) offered by PTU in Distance Learning Mode.
Source-PTU
PTU Syllabus B.Sc. Biotechnology (BSCBT)
SEMESTER I
BSCBT-101: Introductory Biotechnology
Unit I
Introduction: What is Biotechnology?
What is agriculture?
What is biology?
What is biotechnology?
History of biotechnology?
What do you do with it?
Why do it?
Who does it?
Science method to solve a problem.
The role of biotechnology in our society.
The role of genetic variation and natural selection in evolution.
Applications of biotechnology
Careers in biotechnology.
Unit II
Biochemistry and the Cell
Atoms, Elements, Compounds
Chemical bonds
Life's key elements
Relate 5 key elements to the essential compounds of all living organisms.
Chemical reactions
Organic compounds
Proteins, Carbohydrates, Lipids, Nucleic Acids
Compare and contrast the role of Proteins, Carbohydrates, Lipids, and Nucleic Acids in life.
Enzymes
Explain the role of enzymes in living organisms.
Carbon - Oxygen cycle
Cells & Basic structure
Identify and locate cell structures and relate them to their functions.
Using energy
Discover the importance of glucose to living organisms.
Fermentation
Using a microscope to compare different types of cells.
Unit III
Molecular Biology
Nucleotides
Key elements and molecules
The structure of DNA.
Base pairing
The way in which genetic material is copied.
DNA and RNA
Describe the structure and function of RNA as is relates to protein synthesis.
Explain how proteins are made.
Replication, Transcription, Translation and Protein Synthesis
TLW--Extract DNA from known substances.
Restriction enzymes
The value of gel electrophoresis in learning the genetic code.
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Amplification & Cloning
Unit IV
Genetics
Genes and Inheritance
Genes and DNA
Relate genes and heredity to DNA.
Discover patterns of inheritance in living organisms.
Homozygous and Heterozygous
Dominance and Recessiveness
Punnet squares
F1, F2, F...
Using a
Punnet Square to determine patterns of inheritance in monohybrid (1-factor) and dihybrid (2-
Punnet Square to determine patterns of inheritance in monohybrid (1-factor) and dihybrid (2-
factor) crosses.
Problem solving
Using a computer model to solve genetic/heredity problems.
Isolate and fingerprint DNA to discover the infinite potential of the genetic code.
Karyotype chromosomes to discover how sex and certain diseases are inherited.
Disease and disorders
Genetic counseling
Unit V
Microbiology
Bacteria and viruses as pathogens
The characteristics of bacteria.
The characteristics of viruses.
Hharmful versus helpful bacteria and viruses
Antigen and Antibody
Understanding how the immune system combats pathogens.
Cultures, Sterile techniques
Using sterile techniques to culture bacteria.
Transformation, Plasmids and Conjugation
Engineering with microbes
Why bacteria and viruses are essential tools of biotechnology.
Immune system
How the immune response is used in the development of consumer products, industry, and medicine.
Unit VI
Applications of Biotechnology
Plants
Plant systems
The anatomical and physical development of plants.
Photosynthesis / Respiration
Sexual vs. Asexual Reproduction
Describe the principles of sexual and asexual reproduction in plants.
Propagate plant tissue using tissue culture techniques.
Animals
Animal systems
The anatomical and physical development of animals.
Digestion / Rumination
the digestion process in a ruminant animal.
The principles of reproductions in animals.
Reproduction Technologies
* Artificial Insemination
* Embryo Transfer
* Embryo Sexing
* Cloning Embryos
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The process of embryo sexing, splitting, and cloning.
Recombinant DNA
* BST
* Genetic Engineering in Animals
appropriate techniques in setting up animal tissue cultures.
Food Science
Food composition
Food safety
Food preservation
How biotechnology is used to insure the safety of food and food processing.
The role of biotechnology in consumer foods.
Fermentation
* industrial
* traditional
Medical
Antibody
Antigen
Using the interactions between antigen and antibody to determine hormone levels.
Vaccines
How vaccines provide immunity to diseases.
Infectious diseases
Viruses
Blood typing
Describe the production, use, and abuse of antibiotics.
Describe the current research being done on HIV and cancer.
The Human Genome Project
The Human Genome
Goals of the Human Genome Project
Genetic Linkage Maps
Polymorphic DNA Markers
Physical Maps
Sequence - Tagged Sites
Integrating Genetic Linkage
DNA Sequencing
Ethical, Legal and Social Implications
Unit VIII
Ethical Issues and the Future
The positives, negatives, and importance of biotechnology.
What are the issues?
Is there a right and wrong?
Crime / forensics & DNA?
Super humans and eugenics
Is Jurassic Park
Environmental impact / "over-engineering"
Saving endangered species
Current issue in biotechnology.
The ethics of genetic engineering and biotechnology.
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SEMESTER I
BSCBT-102: General Microbiology
Unit I
Microscope (optical, TEM and SEM)
Experiments of Pasteur's.
Sterilization : Methods (Dry heat, wet heat, radiation and chemical etc.).
Unit II
Various forms of Microorganism (PPLOs, Cocci, bacilli and spirilla)
Concept of stains.
Microbial cell wall. Gram positive and gram negative bacteria.
Unit III
Prokaryotic and Eukaryotic microbial cells.
Gene transfer in micro-organism.
Nutritional classification of micro-organism.
Unit IV
Classification and their role in bioprocesses of Biomolecules.
Molecules involved in generation of mechanical stability - papetidoglycans, polysaccharides.
- Membrane lipids.
Unit V
Molecular involved in information storage and retrieval - nucleic acid.
Molecules executing mediator and catalytic functions - the protein.
PRACTICAL
Sugar in given sample.
Extraction and separation of lipids.
Estimation of Protein.
Cleaning of glassware and sterilization.
Preparation of media.
Microbes from hands, tooth - scum and other body parts.
Identification of isolation bacteria (Gram Staining or other staining methods.
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SEMESTER I
BSCBT-103: Biochemistry
Unit I
(i) Introduction to Biochemistry and role of medical microbiologist.
(ii) Ethics.
(iii) Safety measure and hazards in clinical biochemistry lab and first aid.
Unit II
(i) Basic aspects of Bioenergetics.
(ii) Entropy, enthalpy and concept of free energy.
(iii) Thermodynamic law first and second.
Unit III
(i) Carbohydrate : Structure, properties, chemical reactions and functions.
(ii) Amino acid : Essential and nonessential amino acids with structure and function.
(iii) Proteins : Primary, Secondary Tertiory and Quaternary (overview)
Unit IV
(i) Lipids : classification and properties.
(ii) Enzyme : Classification, mechanism of enzyme action, catalyzed reaction.
(iii) Enzyme inhibition.
Unit V
(i) Nucleic Acid : Structure of purine and pyrimidine bases, Nucleotide and Nucleosides.
(ii) DNA and RNA structure and properties.
(iii) Vitamins (Fat and water soluble).
Practical
(i) Blood glucose and its determination by different methods.
(ii) Glucose tolerance test. (GTT)
(iii) Estimation of blood urea.
(iv) Estimation of blood creatinine.
(v) Estimation of blood cholestrol.
(vi) Estimation of serum calcium and phosphorus.
(vii) Estimation of plasma protein.
(viii) Determination of Protein in Urine.
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SEMESTER I
BSCBT-104: Introductory Biology
Unit I
Living World
Biology & Its Branches; relationships with other sciences; scientific methods in Biology;
historical breakthroughs; scope of biology and career options; role of Biology in dispelling
myths and misbelieves; characters of living organisms, (elementary idea of metabolism,
transfer of energy at molecular level, open and closed systems, omoeostasis, growth and
reproduction, adaptation, survival, death).
Origin and evolution of life - theories of evolution; evidence of evolution; sources of variations
( mutation, recombination, genetic drift, migration, natural selection); concept of species;
specification and isolation (geographical and reproductive); origin of species.
Unit II
Diversity of Life
Variety of living organisms, Systematic; need, history and types of classification (artificial,
natural, polygenetic); biosystematics; binomial nomenclature; Two kingdom system, Five
kingdom System, their merits and demerits, status of bacteria and virus; botanical gardens and
herbia; zoological parks and museums.
Unit III
Cell and Cell Division
Cell as a basic unit of life - discovery of cell, cell theory, cell as a self - contained unit;
procaryotic and eukaryotic cell; unicellular and multicellular organisms; tools and techniques (
compound microscope, electron microscope and cell fractionation); Ultrastructure of
prokaryoytic and eukaryotic cell - cell wall, cell membrane - unit membrane concept (flauid
mosaic model); membrane transport; cellular movement (exocytosis, endocytosis); cell
organelles and their functions
- nucleus, mitochondria, plastids, endoplamasic reticulum, Gogli complex, lysosomes,
lysosomes, microtubules, centriole, vacuole, cytoskeleton,
cilia and flagella, ribosomes.
Molecules of cell; inorganic and organic materials - water, salt, mineral ions, carbohydrates,
lipids, amino acids, proteins, nucleotides, nycleic acids (DNA and RNA);
Enzymes (Properties, chemical nature and mechanism of action); vitamins, hormones and
steroids.
Unit IV
Genetics
Continuity of life - heredity, variation; mendel's laws of inheritance, chromosomal basis of
inheritance; other patterns of inheritance - incomplete dominance, multiple allelism,
quantitative inheritance.
Chromosomes - bacterial cell and eukaryotic cell; parallelism between genes and
chromosomes; genome, linkage and crossing over; gene mapping; recombination; sex
chromosomes; sex determination; sex linked inheritance; mutation and chromosomal
aberrations; Human genetics - methods of study, genetic disorders.
DNA as a genetic material - its structure and repliaction; structure of RNA and its role in
protein synthesis; Gene expression - transcription and translation in prokaryotes and
eukaryotes; regulation of gene expression, induction and repression - housekeeping genes;
nuclear basis of differentiation and development; oncoenes.
Basics of Recombinant DNA technolgy; cloning; gene bank; DNA fingerprinting; genomics -
principles and applications, transgenic plants, animals and microbes.
Unit V
Morphology of Plants and Animals
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Morphology - root, stem and leaf, their sturucture and modification; Inflorescence, flower,
fruit, seed and their types;Description of Poaceae, Liliaceae, Fabaceae, Solanaceae,
Brassicaceae and Asteraceae.
Morphology of animals - salient features of earthworm, cockroach and rat; tissue systems,
structure and function of tissues - epithelial, connective, muscular and nervious.
Practical
1. Study of parts of Compound Microsope
2. Study of mitosis in onion root tip and animal cell (grasshopper)
3. Study of meiosis in onion flower buds, and testis iof grasshopper.
4. Study of cyclosis in leaf cell of Hydrilla, or Tradescantia and in Paramoecium.
5. Study of cell wall components ( cellulose, lignin, suberin and mucilage).
6. Study of mitochondria by staining with a Janus Green.
7. Study of specimens and their identification with reason - Bacteria, Oscillator, Spirogyra, Rhizopus,
mushroom/bracket fungi, yeast, liverwort, moss, fern, Pinus, one monocotyledon, one dicotyledon and
lichens.
8. Study of characters of specimens and identification with reason - Amoeba, Hydra, Liver - Fluke,
Ascaris, Leech, Earthworm, Prawn, Silk moth honey bee, snail, Starfish, Dogfish, Rohu, Frog, Lizards,
Pigeon/ any other bird and rabbit/ any other mammal.
9. Study of squamous epithelium, muscle fibres, nerve cells and mammalian blood film through
temporary/permanent slides.
10. Study of external morphology of earthworm, cockroach, from and rat through models.
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SEMESTER I
BSCBT-105: Communication & Soft Skills
UNIT I
Essentials of Grammar:
• Parts of Speech
• Punctuation
• Vocabulary Building
• Phonetics
UNIT II
Office Management:
• Types of Correspondence
• Receipt and Dispatch of Mail
• Filing Systems
• Classification of Mail.
• Role & Function of Correspondence
• MIS
• Managing Computer
UNIT III
Letter & Resume Writing:
• Types of Letters-Formal / Informal
• Importance and Function
• Drafting the Applications
• Elements of Structure
• Preparing the Resume
• Do’s & Don’ts of Resume
• Helpful Hints
UNIT IV
Presentation Skills:
• Importance of Presentation Skills
• Capturing Data
• Voice & Picture Integration
• Guidelines to make Presentation Interesting
• Body Language
• Voice Modulation
• Audience Awareness
• Presentation Plan
• Visual Aids
• Forms of Layout
• Styles of Presentation.
UNIT V
Interview Preparation:
• Types of Interview
• Preparing for the Interviews
• Attending the Interview
• Interview Process
• Employers Expectations
• General Etiquette
• Dressing Sense
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• Postures & Gestures
UNIT VI
Group Discussion & Presentation:
• Definition
• Process
• Guidelines
• Helpful Expressions
• Evaluation
(Note: Every student shall be given 15 minutes. of presentation time & 45 minutes of discussion
on his/ her presentation.)
The student will be evaluated on the basis of :
􀂄 his / her presentation style
􀂄 Feedback of Faculty & Students
􀂄 General Etiquette
􀂄 Proficiency in Letter Drafting / Interview Preparation
􀂄 The paper is internal and at least 3 tests will be taken. Best 2 of 3 shall account for
final grades (70% Test & 30% Presentation)
SEMESTER I
BSCBT-106: Practical
Introductory Biotechnology - 10 Marks
General Microbiology - 15 Marks
Biochemistry - 25 Marks
Introductory Biology - 25 Marks
Internal Assessment: 25 Marks
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SEMESTER II
BSCBT-201: Genetic Taxonomy & Genome
Unit I
Nature of gene : chemical nature.
Gene cistron relationship in Prokaryotes and eukaryotes.
Gene families and pseudogens.
Unit II
Overlapping gene.
Transgenes.
Transposable elements.
Unit III
Gene Mutation.
Physical and Chemical Mutagens.
Molecular Mechanism.
Unit IV
Gene organisation (Principle)
Separation Techniques : Northern and Southern.
Unit V
Gene libraries
Ligation and selection technique.
Selection by genetic recombination.
SEMESTER II
BSCBT-202: Enzymology
Unit I
Enzyme : Introduction, classification, Protein and non protein enzymes.
Catalystic reaction of enzyme.
Kinetics of enzyme.
Unit II
In vitro activity of purified enzymes and their applications in industry.
Enzyme uses in food processing, medicine, diagnostics and production of new compounds.
Enzymes as research tool - modification of biological compounds with the help of enzyme.
Practical
Assays of Enzyme diagnostic.
Kinetic studies on enzymes.
SEMESTER II
BSCBT-203: Immunology
Unit I
Immune system :
Immunity
Organs of the immune system with function.
Unit II
Antigen - Antibody and their structure.
Antigen antibody interaction.
Unit III
Humoral immunity.
Cell mediated immunity (role of MHC and genetic restriction).
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Practical
Purification of antigens.
Purification of antibodies.
Conjugation and labeling of antibodies.
ELISA
RIA
SEMESTER II
BSCBT-204: Genetic Engineering
Unit I
Concept of gene.
Structure of gene.
Significance of gene.
Unit II
Introduction of Genetic Engineering.
Tools of Genetic Engineering : Vectors and Enzyme.
Laboratory requirement and Safety of Genetic Engineering techniques.
Unit III
Introduction of Gene cloning.
Purification and digestion of DNA.
Insertion of DNA into vectors.
Unit IV
Insertion of recombinant DNA into host.
Identification of hybrid clone.
Unit V
Genetic Engineering in Plants : Molecular breeding.
Genetic Engineering in Medicine : Gene Therapy.
Genetic Engineering in Forensic Science : DNA finger Printing.
SEMESTER II
BSCBT-205: Practical
Genetic Taxonomy & Genes : 20 Marks
Enzymology : 20 Marks
Immunology : 15 Marks
Genetic Engineering : 20 Marks
Internal Assessment: 25 Marks
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SEMESTER III
BSCBT-301: Fermentation Techniques
Unit I
Introduction : Fermentation, Fermentor.
Design of Fermentor.
Unit II
Local condition with in a fermentor.
Ideal Fermentor.
Unit III
Types of Fermentors (Principle and Parts)
Batch fermentor (BF)
Continuous stirred-tank Fermentor (CSTF)
Unit IV
Tubular Fermentor (TF) (Principle and parts)
Fluidiced bed Fermentor (FBF)
Unit V
Computer control of fermentation processes :
Introduction.
Instrument.
Computer application in Fermentation Technology.
SEMESTER III
BSCBT-302: Cell Biology
Unit I
Cell structure : Prokaryotic and Eukaryotic.
Structure of Plasma membrane with different models.
Structure of cell organelles (overview)
Unit II
Structure of chromosome.
Structure of DNA and types.
Different types of RNA.
Unit III
Cell Division : Mitosis.
Meosis : The reduction division.
Significance of DNA.
Practical
Cell counting method - haemocytometer.
Cytological preparations - Fixation, dehydration
Staining.
Squash in stain.
Embedding and sectioning.
Separation of cell types (from blood)
Separation of cell organelles.
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SEMESTER III
BSCBT-303: Tissue Culture
Unit I
Introduction of Tissue culture.
History of development.
Primary and secondary culture.
Unit II
Growth kinetics and organ culture.
Application of Tissue culture for gene expression.
SEMESTER III
BSCBT-304: Molecular Biology
Unit I:- Cell:- Cell organelles: Structure function, structure of mitochondria and organization of
respiratory chain, organization of cytoskeleton and nucleic.
Unit -II:- STRUCTURE & PROPERTIES OF DNA
Discovery of DNA as the genetic material, Structure of DNA (A,B&Z forms ), concept & definition of the
genome, C-value paradox, denaturation & renaturation of DNA, repetitive & non-repetitive DNA,
reassociation kinetics. Cot curve, Rot curve, chemical & kinetic complexitv of DNA, supercoiling in
DNA.
Unit -III :- PROKARYOTIC AND EUKARYOTIC GENOME ORGANIZATION:-Organization of viral genome,
organization of bacterial genome, chromosome structure in eukaryotes, nucleosome model, chromatin
structure, satellite DNA, polytene chromosomes, lampbrush chromosomes, B chromosomes-Evolution
of the gene concept, definition of gene, interrupted genes, multigene families & pseudogenes,
overlapping genes, nested genes, open reading frames.
Unit-IV:-DNA REPLICATION:- General features of DNA replication in prokaryotes & eukaryotes,
enzymology of DNA replication, regulation of DNA replication
Unit-V:- GENE MUTATION, REPAIR & RECOMBINATION:-Definition & types of mutation, mutagenic
agents & their mode of action, reversion & suppression of mutation.
DNA repair mechanisms : light dependent repair, excision repair, mis-match repair Post-replication
repair, sos response.
DNA recombination mechanisms : holiiday model, Rec A, Rec BCD, gene conversion
SEMESTER III
BSCBT-305: Practical
Fermentation Techniques : 20 Marks
Cell Biology : 25 Marks
Tissue Culture : 20 Marks
Molecular Biology : 15 Marks
Internal Assessment : 25 Marks
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SEMESTER IV
BSCBT-401: Bio-chemical Techniques
Unit I
Nature of Biological material.
General properties of organic compounds.
Hydrophilic and Hydrophobic groups in biological molecules.
Unit II
Perspectives of biological macromolecules : the repeating units in nucleic acids and proteins.
Helicity, bending, looping, pleats, salt bridges and their determents.
The basis for intermolecules interaction eg : enzyme substract and antigen antibody recognition.
Unit III
Energetics of a living body.
Principle of Colorimetry and spectrophotometer.
Strategies of light reception in microbes :- Plant and animals.
Unit IV
Intra and intermolecular interactions in biological systems.
Spatial and charge compatibility as determination of such interaction.
Unit V
General spectroscopy of
UV-Vis
Fluorescence
Atomic absorption
SEMESTER IV
BSCBT-402: Bio-physical Techniques
Unit I
Principle & application of Light Microscope
Phase Contrast Microscope
Fluorescence Microscope
SEM & TEM
Unit II
Principles & applications of paper chromatography
Thin layer chromatography
Affinity & Ion Exchange Chromatography
HPLC
Fixation Staining
Unit III
Principles of biophysical methods used for analysis of biopolymer structure.
X-ray diffraction, NMR & ESR spectroscopy
Unit IV
Principles and Applications of traces techniques in Biology
Radiation dosimetry
Radioactive isotopes & half life on isotopes
Scintillation spectrophotometry
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SEMESTER IV
BSCBT-403: Industrial Biotechnology
Unit I
Application of Biotechnology in Agriculture.
Biofertilizer and Nitrogen fixers.
Bio-pesticides.
Bio-weedicis Biotechnology.
Unit II
Application of Biotechnology in Medicine
Vaccine
Steroids transformation.
Protein formation.
Unit III
Application of Biotechnology in Paper industry and plant petroleum.
Unit IV
Application of Biotechnology in Environment.
Biotechnological inputs in producing good quality national fibres.
Conventional fuel and their environmental impacts.
Plant and animal wastes.
Animal oil
Unit V
Application of Biotechnology in Food Industry.
Beverages.
Bakery
Dairy Product.
INDUSTRIAL APPLICATION PRACTICAL
Study of Products which are manufactured in industry, on the basis of biotechnology principle.
SEMESTER IV
BSCBT-404: Instrumentation
Unit-1 :-
Centrifugation : principle, types, analytical and preparatory centrifugation, differential density
gradient centrifugation, sedimentation and coefficient centrifuge and its application.
Electrophoresis : principles, types and application (paper, starch, polyacrylamide and agarose
electrophoresis.
Chromatography : principle, types and application of paper, thin layer, ion exchange, gas
chromatography and HPLC.
Unit - 2 :-
Microscopy : light, phase contrast, interference & electron microscopy
Radioactivity : saddy-fajans & russel group displacement law, half life period, disintegration or decay
constant, transmutation or disintegration of elements. Radio carbon dating method, application of
transmutation reaction (artificial radioactivity). Geiger muller counter, scintillation, liquid, crystal &
gamma counter.
Unit -3 :-
Basic principles of spectroscopy ; electromagnetic radiations, wave properties & parameters,
electromagnetic spectrum spectroscopic methods in each region, types of spectra & interaction
mechanisms.
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UV-vis spectroscopy, TR spectroscopy, nuclear magnetic resonance spectroscopv (NMR), electron spin
resonance spectroscopy (ESR).
Unit - 4 :-
Atomic spectroscopy - principle, instrumentation, preparation of samples, applications.
Flame photometry.
X-ray crystallography - principle, instrumentation and applications. ORD &. CD ; fundamental
principle, cotton effect, birefringes, refractive indices. Application of ORD & CD for quantitative
analysis, octant rule, haioketone rule. Principle, instrumentation & application of polarimetry,
SEMESTER IV
BSCBT-405: Practical
Bio-Chemical Techniques : 20 Marks
Bio-Physical Techniques : 15 Marks
Industrial Biotechnology : 20 Marks
Instrumentation : 20 Marks
Internal Assessment : 25 Marks
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SEMESTER V
BSCBT-501: Animal Biotechnology
Unit I
General metabolism.
Secondary metabolites/Products (insulin, Growth hormone, Interferon, factor VIII etc.)
Expressing cloned proteins in animal cells, production and processing of chosen protein.
Unit II
Introduction to invitromethod : Terms and definition, growth regulators.
Enbryo culture, embryo rescue after wide hybridization, and its application.
Introduction to the process of embryogenesis and organogenesis and their practical application.
Unit III
Haploids and their application.
Somaclonal variation and application.
Clonal multiplication of elite species.
Practical
Practical application of genetic transformation (theory).
SEMESTER V
BSCBT-502: Plant Biotechnology
Unit I
Introduction to protoplast isolation : Principle and application.
Testing of viability of isolated protoplast.
Various steps in the regeneration of protoplast.
Unit II
Introduction to somatic hybridization.
Various method for fusing protoplast.
Use of markers for selection of hybrid cells.
Practical
Practical application of somatic hybridization (theory).
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SEMESTER V
BSCBT-503: Environmental Biotechnology
Unit I
Renewable and non renewable resources.
Renewable should be bio-assimilable/bio degradable.
Major consumer items : Food, fuel and fibres.
Unit II
Conventional fuel and their environmental impacts.
Firewood
Plant and animal wastes.
Coal
Gas
Animal oil
Unit III
Modern fuels and their environmental impacts.
Methogenic bacteria and biogas.
Microbial hydrogen production.
Conversion of sugars to ethanol.
Cellulose degradation for combustible fuel.
Plant based petroleum industry.
Unit IV
Biotechnological inputs in producing good quality national fibres.
Microbiological quality of food and water.
Unit V
Biofertilizers.
Treatment of municipal waste and industrial effluents.
Degradation of pesticides and other toxic chemicals by micro-orgnism.
Practical
Practical application of tissue and organ culture (summarizing the practical application of all the above mentioned
techniques in paper) only theory.
SEMESTER V
BSCBT-504: Pharmaceutical Biotechnology
Unit I
Production recombinant pharmaceuticals :
Recombinant insulin
Human Growth factor synthesis
Recombinant factor VIII
Unit II
Synthesis of :
Recombinant vaccine
Recombine Protein
Live recombinant vaccine
Unit III
Identification of genes responsible for human disease.
Breast cancer
Autosomal dominant and recessive disorders.
X-linked disorders.
Unit IV
Gene therapy of somatic cell.
Genetic Manipulation of Grem cell.
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Unit V
Prospects and
Ethics of gene therapy
SEMESTER V
BSCBT-505: Practical
Animal Biotechnology : 20 Marks
Plant Biotechnology : 20 Marks
Environmental Biotechnology : 10 Marks
Pharmaceutical Biotechnology : 25 Marks
Internal Assessment : 25 Marks
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SEMESTER VI
BSCBT-601: Bio-informatics
Introduction to Bioinformatics.
Uses of Bioinformatics.
Applications of Bioinformatics
Websites for Bioinformatics.
Fact file of Bioinformatics.
SEMESTER VI
BSCBT-602: Drug Design
Pharmacology.
Drug metabolism.
Pharmacogenetics.
Frontiers in pharmacology.
Unit V
Statistical methods in Pharmacology.
Introduction to Research in pharmacology.
Introduction to Pharmacoinformatics.
SEMESTER VI
BSCBT-603: Research Methodology
Introduction to Research: Definition, Scope, Limitations, and Types.
Objectives of Research
Research Process
Research Designs
Data Collection: Secondary Data, Primary Data, and Methods of Collection.
Scaling Techniques: Concept, Types, Rating scales & Ranking Scales
Scale Construction Techniques, Multi Dimensional Scaling.
Sampling Designs: Concepts, Types and Techniques
Sample Size Decision
Theory of Estimation and Testing of Hypothesis
Small & Large Sample Tests, Tests of Significance based on t, F , Z test and Chi-Square Test.
Designing Questionnaire.
Interviewing.
Tabulation, Coding, Editing.
Interpretation and Report Writing.
SEMESTER VI
BSCBT-604: Information Technology & Bioinformatics
Unit I
Overview of computers.
Operating system and networking concept (Windows, UNIX, Linux)
Basics of internet and websites.
Unit II
MS-Office.
Data structure and Algorithms.
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Bioinformatics Internet Applications
SEMESTER VI
BSCBT-605: Practical
Bio-informatics :20 Marks
Drug Design :15 Marks
Research Methodology :20 Marks
Information Technology & Bioinformatics :20 Marks
Internal Assessment: 25 Marks
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